As the Cannabis market grows for both medical and recreational use, so does the need for standardized quality control within the industry. With regards to Cannabis quality control there are numerous points to consider, from moisture content to pesticide use.
Moisture Content – Cannabis flower moisture content should be tested and controlled to: minimize the chance of mold formation; control microbiological levels; ensure proper drying, curing and storage conditions; and support product life expectancy. Some manufacturing processes for marijuana quality control procedures also require a certain water content in the starting material.
Terpenoids and Cannabinoids Analysis
The amount of terpenoids and cannabinoids in the starting material determines the most appropriate industrial processing method and which final cannabis product will likely be manufactured. This analysis is usually carried out using LC-MS (Liquid Chromatography Mass Spectrometry) or GC (Gas Chromatography). LC-MS and GC demand a flow of inert gas like hydrogen or nitrogen, both of which can be easily supplied via a gas generator. Uncover more concerning the Peak Scientific range of gas generators for GC & LC-MS here.
Pesticides and Herbicides – Similar to other agricultural crops and products meant for human consumption, Cannabis plants needs to be tested for herbicides and pesticides. Detecting pesticides and herbicides can be difficult as a result of complexity of cannabis material. GCMS (Gas Chromatography Mass Spectrometry) is generally used for this function.
Microbiological Screening – Medical Cannabis is often employed for HIV and cancer patients where patient’s defense mechanisms has been compromised. Therefore, high microbial levels or pathogenic micro-organisms might be life threatening. It is important then that several Mycotoxins and fungus types needs to be detected as part of cannabis quality control and release specifications.
Residual Solvents – Where solvents have been used as an element of Cannabis product processing, solvent residuals inside the final products ought to be tested to make sure that they satisfy the accepted criteria. The FDA has published zvqtob criteria for residual solvents in APIs for pharmaceutical use.
Chemical Toxins – Like various other plants, Cannabis draws metals through the earth. It is therfore essential to test for Mercury, Lead, Arsen and Cadmium.
Cannabinoid Concentration – Concentration ranges for cannabinoids such as THC,THCa, CBD, CBDa, CBN, CBC, CBG should match the ranges specified on the product label, according to product usage purpose, patient’s medical condition, age etc. Cannabinoid concentrations could be tested using LC-MS (Liquid Chromatography Mass Spectrometry) and HPLC (High Performance Liquid Chromatography) . There are a wide range of Peak Scientific nitrogen gas generators designed specifically for LC-MS, available here.
Terpene Concentration – Terpenes increase cannabinoids’ therapeutic effects and are acknowledged to get their own health benefits, they also play a role in Cannabis taste and aroma. They may be detected using GC.
Taking the above into account, it is actually clear that there exists a necessity for standarized procedures for every step of the Cannabis analysis and testing process so that you can guarantee safe use. The safest approach to supply cannabis testing laboratories with gas for his or her LC-MS and GC is by gas generators, which usually do not present the safety and health risks related to gas cylinders.